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1

Human umbilical vein endothelium-derived exosomes play a role in foetoplacental endothelial dysfunction in gestational diabetes mellitus

Sáez, Tamara, Salsoso, Rocío, Leiva, Andrea, Toledo, Fernando, de Vos, Paul, Faas, Marijke, Sobrevia, Luis

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2018

Language:

english

File:

PDF, 1.20 MB

english, 2018

2

Is there a role for exosomes in foetoplacental endothelial dysfunction in gestational diabetes mellitus?

Sáez, Tamara, de Vos, Paul, Sobrevia, Luis, Faas, Marijke M.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.20 MB

english, 2018

3

Foetoplacental epigenetic changes associated with maternal metabolic dysfunction

Kerr, Bredford, Leiva, Andrea, Farías, Marcelo, Contreras-Duarte, Susana, Toledo, Fernando, Stolzenbach, Francisca, Silva, Luis, Sobrevia, Luis

Journal:

Year:

2018

Language:

english

File:

PDF, 400 KB

english, 2018

4

Neonates from women with pregestational maternal obesity show reduced umbilical vein endothelial response to insulin

Villalobos-Labra, Roberto, Westermeier, Francisco, Pizarro, Carolina, Sáez, Pablo J., Toledo, Fernando, Pardo, Fabián, Kusanovic, Juan P., Mardones, Francisco, Poblete, José A., Sobrevia, Luis, Farías

Journal:

Year:

2019

Language:

english

File:

PDF, 27.67 MB

english, 2019

5

Nitric oxide reduces adenosine transporter ENT1 gene (SLC29A1) promoter activity in human fetal endothelium from gestational diabetes

Marcelo Farías, Rody San Martín, Carlos Puebla, Jeremy D. Pearson, Javier F. Casado, Marçal Pastor-Anglada, Paola Casanello, Luis Sobrevia

Journal:

Journal of Cellular Physiology

Year:

2006

Language:

english

File:

PDF, 356 KB

english, 2006

6

Insulin restores glucose inhibition of adenosine transport by increasing the expression and activity of the equilibrative nucleoside transporter 2 in human umbilical vein endothelium

Gonzalo Muñoz, Rody San Martín, Marcelo Farías, Luis Cea, Andrea Vecchiola, Paola Casanello, Luis Sobrevia

Journal:

Journal of Cellular Physiology

Year:

2006

Language:

english

File:

PDF, 365 KB

english, 2006

7

D-glucose stimulation of L-arginine transport and nitric oxide synthesis results from activation of mitogen-activated protein kinases p42/44 and Smad2 requiring functional type II TGF-β receptors in human umbilical vein endothelium

Rodrigo Vásquez, Marcelo Farías, José Luis Vega, Rody San Martin, Andrea Vecchiola, Paola Casanello, Luis Sobrevia

Journal:

Journal of Cellular Physiology

Year:

2007

Language:

english

File:

PDF, 273 KB

english, 2007

8

High D-glucose reduces SLC29A1 promoter activity and adenosine transport involving specific protein 1 in human umbilical vein endothelium

Carlos Puebla, Marcelo Farías, Marcelo González, Andrea Vecchiola, Claudio Aguayo, Bernardo Krause, Marçal Pastor-Anglada, Paola Casanello, Luis Sobrevia

Journal:

Journal of Cellular Physiology

Year:

2008

Language:

english

File:

PDF, 341 KB

english, 2008

9

Insulin-stimulated L-arginine transport requires SLC7A1 gene expression and is associated with human umbilical vein relaxation

Marcelo González, Victoria Gallardo, Natalia Rodríguez, Carlos Salomón, Francisco Westermeier, Enrique Guzmán- Gutiérrez, Fernando Abarzúa, Andrea Leiva, Paola Casanello, Luis Sobrevia

Journal:

Journal of Cellular Physiology

Year:

2011

Language:

english

File:

PDF, 670 KB

english, 2011

10

Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and -2 and membrane hyperpolarization in human umbilical vein endothelial cells

Marcelo González, Carlos Flores, Jeremy D. Pearson, Paola Casanello, Luis Sobrevia

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2004

Language:

english

File:

PDF, 378 KB

english, 2004

11

Nitric Oxide, cGMP and cAMP Modulate Nitrobenzylthioinosine-Sensitive Adenosine Transport in Human Umbilical Artery Smooth Muscle Cells from Subjects with Gestational Diabetes

Claudio Aguayo, Luis Sobrevia

Journal:

Experimental Physiology

Year:

2000

Language:

english

File:

PDF, 362 KB

english, 2000

12

Elevated D-glucose induces insulin insensitivity in human umbilical endothelial cells isolated from gestational diabetic pregnancies

L. Sobrevia, D. L. Yudilevich, G. E. Mann

Journal:

The Journal of Physiology

Year:

1998

Language:

english

File:

PDF, 414 KB

english, 1998

13

Regulation of adenosine transport by D-glucose in human fetal endothelial cells: involvement of nitric oxide, protein kinase C and mitogen-activated protein kinase

Viviana P. Montecinos, Claudio Aguayo, Carlos Flores, Amanda W. Wyatt, Jeremy D. Pearson, Giovanni E. Mann, Luis Sobrevia

Journal:

The Journal of Physiology

Year:

2000

Language:

english

File:

PDF, 381 KB

english, 2000

14

Modulation of adenosine transport by insulin in human umbilical artery smooth muscle cells from normal or gestational diabetic pregnancies

Claudio Aguayo, Carlos Flores, Jorge Parodi, Romina Rojas, Giovanni E. Mann, Jeremy D. Pearson, Luis Sobrevia

Journal:

The Journal of Physiology

Year:

2001

Language:

english

File:

PDF, 450 KB

english, 2001

15

Hyperglycaemia Inhibits Thymidine Incorporation and Cell Growth via Protein Kinase C, Mitogen-Activated Protein Kinases and Nitric Oxide in Human Umbilical Vein Endothelium

Susana Rojas, Romina Rojas, Liliana Lamperti, Paola Casanello, Luis Sobrevia

Journal:

Experimental Physiology

Year:

2003

Language:

english

File:

PDF, 376 KB

english, 2003

16

Nitric Oxide Synthesis Requires Activity of the Cationic and Neutral Amino Acid Transport System y+L in Human Umbilical vein Endothelium

Yerko Arancibia-Garavilla, Fernando Toledo, Paola Casanello, Luis Sobrevia

Journal:

Experimental Physiology

Year:

2003

Language:

english

File:

PDF, 293 KB

english, 2003

17

Role of adenosine transport in gestational diabetes-induced l-arginine transport and nitric oxide synthesis in human umbilical vein endothelium

Gustavo Vásquez, Felipe Sanhueza, Rodrigo Vásquez, Marcelo González, Rody San Martín, Paola Casanello, Luis Sobrevia

Journal:

The Journal of Physiology

Year:

2004

Language:

english

File:

PDF, 257 KB

english, 2004

18

Adenosine plasma levels in the fetoplacental circulation in preeclampsia

Carlos Escudero, Luis Sobrevia

Journal:

American Journal of Obstetrics and Gynecology

Year:

2012

Language:

english

File:

PDF, 130 KB

english, 2012

19

Adenosine mediates transforming growth factor-beta 1 release in kidney glomeruli of diabetic rats

H. Roa, C. Gajardo, E. Troncoso, V. Fuentealba, C. Escudero, A. Yáñez, L. Sobrevia, M. Pastor-Anglada, C. Quezada, R. San Martin

Journal:

Year:

2009

Language:

english

File:

PDF, 3.08 MB

english, 2009

20

Equilibrative nucleoside transporter 2 is expressed in human umbilical vein endothelium, but is not involved in the inhibition of adenosine transport induced by hyperglycaemia

C. Aguayo, J. Casado, M. González, J.D. Pearson, R.San Martín, P. Casanello, M. Pastor-Anglada, L. Sobrevia

Journal:

Year:

2005

Language:

english

File:

PDF, 465 KB

english, 2005

21

Gestational diabetes and the adenosine/l-Arginine/nitric oxide (ALANO) pathway in human umbilical vein endothelium

R. San Martín, L. Sobrevia

Journal:

Year:

2006

Language:

english

File:

PDF, 287 KB

english, 2006

22

A Hypothesis for Preeclampsia: Adenosine and Inducible Nitric Oxide Synthase in Human Placental Microvascular Endothelium

C. Escudero, L. Sobrevia

Journal:

Year:

2008

Language:

english

File:

PDF, 666 KB

english, 2008

23

Human Equilibrative Nucleoside Transporters 1 and 2 may be Differentially Modulated by A2B Adenosine Receptors in Placenta Microvascular Endothelial Cells from Pre-eclampsia

C. Escudero, P. Casanello, L. Sobrevia

Journal:

Year:

2008

Language:

english

File:

PDF, 908 KB

english, 2008

24

Reduced l-Arginine Transport and Nitric Oxide Synthesis in Human Umbilical Vein Endothelial Cells from Intrauterine Growth Restriction Pregnancies is Not Further Altered by Hypoxia

P. Casanello, B. Krause, E. Torres, V. Gallardo, M. González, C. Prieto, C. Escudero, M. Farías, L. Sobrevia

Journal:

Year:

2009

Language:

english

File:

PDF, 647 KB

english, 2009

25

Differential expression of functional nucleoside transporters in non-differentiated and differentiated human endothelial progenitor cells

E. Guzmán-Gutiérrez, C. Sandoval, E. Nova, J.L. Castillo, J.C. Vera, L. Lamperti, B. Krause, C. Salomón, C. Sepúlveda, C. Aguayo, L. Sobrevia

Journal:

Year:

2010

Language:

english

File:

PDF, 789 KB

english, 2010

26

Preface

Journal:

Year:

2011

Language:

english

File:

PDF, 104 KB

english, 2011

27

Review: Differential placental macrovascular and microvascular endothelial dysfunction in gestational diabetes

L. Sobrevia, F. Abarzúa, J.K. Nien, C. Salomón, F. Westermeier, C. Puebla, F. Cifuentes, E. Guzmán-Gutiérrez, A. Leiva, P. Casanello

Journal:

Year:

2011

Language:

english

File:

PDF, 329 KB

english, 2011

28

Hypoxia-reduced nitric oxide synthase activity is partially explained by higher arginase-2 activity and cellular redistribution in human umbilical vein endothelium

C.P. Prieto, B.J. Krause, C. Quezada, R. San Martin, L. Sobrevia, P. Casanello

Journal:

Year:

2011

Language:

english

File:

PDF, 1.25 MB

english, 2011

29

Role of arginase-2 and eNOS in the differential vascular reactivity and hypoxia-induced endothelial response in umbilical arteries and veins

B.J. Krause, C.P. Prieto, E. Muñoz-Urrutia, S. San Martín, L. Sobrevia, P. Casanello

Journal:

Year:

2012

Language:

english

File:

PDF, 800 KB

english, 2012

30

Nitric oxide reduces transcriptional promoter activity of SLC29A1 for human equilibrative nucleoside transporter 1 in umbilical vein endothelium from gestational diabetes

Marcelo Farias, Rody San Martin, Marcal Pastor-Anglada, Paola Casanello, Luis Sobrevia

Journal:

Vascular Pharmacology

Year:

2006

Language:

english

File:

PDF, 56 KB

english, 2006

31

Effect of A2a purinoceptors stimulation on l-arginine transport and nitric oxide synthesis in placental microvascular endothelial cells from women with preeclampsia

Carlos Escudero, Paola Casanello, Luis Sobrevia

Journal:

Vascular Pharmacology

Year:

2006

Language:

english

File:

PDF, 54 KB

english, 2006

32

d-glucose increased l-arginine transport and nitric oxide synthesis through an autocrine mechanism involving TGF-β1 and TGF-β receptor II (TβRII) in human umbilical vein endothelium

Rodrigo Vasquez, Marcelo Farias, Rody San Martin, Paola Casanello, Luis Sobrevia

Journal:

Vascular Pharmacology

Year:

2006

Language:

english

File:

PDF, 65 KB

english, 2006

33

Affect of diabetes in human trophoblast and umbilical endothelium: Transport and metabolism of adenosine (ADO) and L-arginine (NO synthesis)

L. Sobrevia, G.E. Mann, D. Yudilevich

Journal:

Year:

1996

Language:

english

File:

PDF, 148 KB

english, 1996

34

New therapeutic approaches to treating hypertension in pregnancy

Alfonso Mate, Carmen M. Vázquez, Andrea Leiva, Luis Sobrevía

Journal:

Drug Discovery Today

Year:

2012

Language:

english

File:

PDF, 1.04 MB

english, 2012

35

Kinetics and specificity of l-alanine transport across the basolateral cell surface in isolated oxyntic glands

Ivan Bravo, Luis Sobrevia

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1990

Language:

english

File:

PDF, 570 KB

english, 1990

36

Uptake of l-leucine and l-phenylalanine across the basolateral cell surface in isolated oxyntic glands

Luis Sobrevía, Vivian Medina, Karin Reinicke, Iván Bravo

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1992

Language:

english

File:

PDF, 487 KB

english, 1992

37

Adenosine A2B receptor mediates an increase on VEGF-A production in rat kidney glomeruli

D. Valladares, C. Quezada, P. Montecinos, Concha II, A.J. Yañez, L. Sobrevia, R. San Martín

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 391 KB

english, 2008

38

Adenosine and glucose transport in diabetic human and rat placenta

L. Sobrevía, N. Osses, G. Carrasco, M. Muñoz, D.L. Yudilevich

Journal:

Year:

1993

Language:

english

File:

PDF, 69 KB

english, 1993

39

5′-ectonucleotidase mediates multiple-drug resistance in glioblastoma multiforme cells

Quezada, Claudia, Garrido, Wallys, Oyarzún, Carlos, Fernández, Katia, Segura, Rodrigo, Melo, Rómulo, Casanello, Paola, Sobrevia, Luis, San Martín, Rody

Journal:

Journal of Cellular Physiology

Year:

2013

Language:

english

File:

PDF, 382 KB

english, 2013

40

Gestational Diabetes - Causes, Diagnosis and Treatment || Pro-Inflammatory Cytokines, Lipid Metabolism and Inflammation in Gestational Diabetes Mellitus as Cause of Insulin Resistance

Year:

2013

Language:

english

File:

PDF, 386 KB

english, 2013

41

Role of Insulin and Adenosine in the Human Placenta Microvascular and Macrovascular Endothelial Cell Dysfunction in Gestational Diabetes Mellitus

Guzmán-Gutiérrez, Enrique, Arroyo, Pablo, Salsoso, Rocío, Fuenzalida, Bárbara, Sáez, Tamara, Leiva, Andrea, Pardo, Fabián, Sobrevia, Luis

Journal:

Microcirculation

Year:

2014

Language:

english

File:

PDF, 345 KB

english, 2014

42

Placental cell-derived exosomes increase in maternal circulation with gestational age

Salomon, Carlos, Torres, Maria Jose, Illanes, Sebastián, Kobayashi, Miharu, Sobrevia, Luis, Ashman, Keith, Mitchell, Murray, Rice, Greg

Journal:

Year:

2013

Language:

english

File:

PDF, 60 KB

english, 2013

43

Role of equilibrative adenosine transporters and adenosine receptors as modulators of the human placental endothelium in gestational diabetes mellitus

Pardo, F., Arroyo, P., Salomón, C., Westermeier, F., Salsoso, R., Sáez, T., Guzmán-Gutiérrez, E., Leiva, A., Sobrevia, L.

Journal:

Year:

2013

Language:

english

File:

PDF, 534 KB

english, 2013

44

Maternal Hypercholesterolemia in Pregnancy Associates With Umbilical Vein Endothelial Dysfunction: Role of Endothelial Nitric Oxide Synthase and Arginase II

Leiva, A., de Medina, C. D., Salsoso, R., Saez, T., San Martin, S., Abarzua, F., Farias, M., Guzman-Gutierrez, E., Pardo, F., Sobrevia, L.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2013

Language:

english

File:

PDF, 1.37 MB

english, 2013

45

TGF- 1 inhibits expression and activity of hENT1 in a nitric oxide-dependent manner in human umbilical vein endothelium

Vega, J. L., Puebla, C., Vasquez, R., Farias, M., Alarcon, J., Pastor-Anglada, M., Krause, B., Casanello, P., Sobrevia, L.

Journal:

Cardiovascular Research

Year:

2009

Language:

english

File:

PDF, 332 KB

english, 2009

46

Insulin requires normal expression and signaling of insulin receptor A to reverse gestational diabetes-reduced adenosine transport in human umbilical vein endothelium

Westermeier, F., Salomon, C., Farias, M., Arroyo, P., Fuenzalida, B., Saez, T., Salsoso, R., Sanhueza, C., Guzman-Gutierrez, E., Pardo, F., Leiva, A., Sobrevia, L.

Journal:

The FASEB Journal

Year:

2015

Language:

english

File:

PDF, 1.28 MB

english, 2015

47

Insulin Restores Gestational Diabetes Mellitus-Reduced Adenosine Transport Involving Differential Expression of Insulin Receptor Isoforms in Human Umbilical Vein Endothelium

Westermeier, F., Salomon, C., Gonzalez, M., Puebla, C., Guzman-Gutierrez, E., Cifuentes, F., Leiva, A., Casanello, P., Sobrevia, L.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.36 MB

english, 2011

48

Insulin restores l-arginine transport requiring adenosine receptors activation in umbilical vein endothelium from late-onset preeclampsia

Salsoso, R., Guzmán-Gutiérrez, E., Sáez, T., Bugueño, K., Ramírez, M.A., Farías, M., Pardo, F., Leiva, A., Sanhueza, C., Mate, A., Vázquez, C., Sobrevia, L.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.60 MB

english, 2015

49

Dexamethasone and rosiglitazone are sufficient and necessary for producing functional adipocytes from mesenchymal stem cells

Contador, D., Ezquer, F., Espinosa, M., Arango-Rodriguez, M., Puebla, C., Sobrevia, L., Conget, P.

Journal:

Experimental Biology and Medicine

Year:

2015

Language:

english

File:

PDF, 1.67 MB

english, 2015

50

Insulin therapy and fetoplacental vascular function in gestational diabetes mellitus

Sobrevia, Luis, Salsoso, Rocío, Sáez, Tamara, Sanhueza, Carlos, Pardo, Fabián, Leiva, Andrea

Journal:

Experimental Physiology

Year:

2015

Language:

english

File:

PDF, 539 KB

english, 2015

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